重组人表皮细胞生长因子
rhEGF
产品编号 :
CAS No. :
品牌 :
分子式 :
分子量 :
性状 :
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基础信息
| 中文名称 | 重组人表皮细胞生长因子 |
|---|---|
| 英文名称 | rhEGF |
| Cas No. | 62253-63-8 |
| 精确分子量 | 6,217.74465 |
| Smiles | S([H])C([H])([H])[C@@]([H])(C(N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(N([H])[C@]([H])(C(N([H])[C@]([H])(C(N([H])[C@]([H])(C(N([H])[C@]([H])(C(N([H])C([H])([H])C(N([H])[C@]([H])(C(N([H])[C@]([H])(C(N([H])[C@]([H])(C(N([H])[C@]([H])(C(N([H])[C@]([H])(C(N([H])C([H])([H])C(N([H])[C@]([H])(C(N([H])[C@@]([H])(C([H])([H])S[H])C(N([H])[C@@]([H])(C([H])([H])C([H])([H])SC([H])([H])[H])C(N([H])[C@@]([H])(C([H])([H])C1C([H])=C([H])C(O[H])=C([H])C=1[H])C(N([H])[C@]([H])(C(N([H])[C@]([H])(C(N([H])[C@@]([H])(C([H])([H])[H])C(N([H])[C@]([H])(C(N([H])[C@@]([H])(C([H])([H])C(=O)O[H])C(N([H])[C@]([H])(C(N([H])[C@]([H])(C(N([H])[C@@]([H])(C([H])([H])[H])C(N([H])[C@@]([H])(C([H])([H])S[H])C(N([H])[C@@]([H])(C([H])([H])C(N([H])[H])=O)C(N([H])[C@@]([H])(C([H])([H])S[H])C(N([H])[C@]([H])(C(N([H])[C@]([H])(C(N([H])C([H])([H])C(N([H])[C@@]([H])(C([H])([H])C1C([H])=C([H])C(O[H])=C([H])C=1[H])C(N([H])[C@]([H])(C(N([H])C([H])([H])C(N([H])[C@@]([H])(C([H])([H])C([H])([H])C(=O)O[H])C(N([H])[C@]([H])(C(N([H])[C@@]([H])(C([H])([H])S[H])C(N([H])[C@@]([H])(C([H])([H])C([H])([H])C(N([H])[H])=O)C(N([H])[C@@]([H])(C([H])([H])C1C([H])=C([H])C(O[H])=C([H])C=1[H])C(N([H])[C@]([H])(C(N([H])[C@@]([H])(C([H])([H])C(=O)O[H])C(N([H])[C@]([H])(C(N([H])[C@]([H])(C(N([H])[C@]([H])(C(N([H])[C@]([H])(C(N([H])[C@]([H])(C(N([H])[C@]([H])(C(N([H])[C@]([H])(C(=O)O[H])C([H])([H])C([H])([H])C([H])([H])N([H])/C(=N/[H])/N([H])[H])=O)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])=O)C([H])([H])C([H])([H])C(=O)O[H])=O)C([H])([H])C1=C([H])N([H])C2=C([H])C([H])=C([H])C([H])=C12)=O)C([H])([H])C1=C([H])N([H])C2=C([H])C([H])=C([H])C([H])=C12)=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])=O)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])=O)=O)C([H])([H])C([H])([H])C([H])([H])N([H])/C(=N/[H])/N([H])[H])=O)=O)=O)=O)C([H])([H])C([H])([H])C([H])([H])N([H])/C(=N\[H])/N([H])[H])=O)=O)=O)[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])=O)=O)=O)C([H])(C([H])([H])[H])C([H])([H])[H])=O)C([H])(C([H])([H])[H])C([H])([H])[H])=O)=O)=O)=O)=O)C([H])([H])C1C([H])=C([H])C(O[H])=C([H])C=1[H])=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])=O)=O)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])=O)=O)C([H])([H])C([H])([H])C(=O)O[H])=O)[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])=O)=O)=O)=O)C([H])(C([H])([H])[H])C([H])([H])[H])=O)=O)C([H])([H])C(=O)O[H])=O)C([H])([H])C1=C([H])N=C([H])N1[H])=O)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])=O)C([H])([H])S[H])=O)C([H])([H])C1C([H])=C([H])C(O[H])=C([H])C=1[H])=O)=O)C([H])([H])C(=O)O[H])=O)C([H])([H])C1=C([H])N=C([H])N1[H])=O)C([H])([H])O[H])=O)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])=O)=O)N([H])C([C@]([H])(C([H])([H])C([H])([H])C(=O)O[H])N([H])C([C@]([H])(C([H])([H])O[H])N([H])C([C@]([H])(C([H])([H])C(=O)O[H])N([H])C([C@]([H])(C([H])([H])O[H])N([H])C([C@]([H])(C([H])([H])C(N([H])[H])=O)N([H])[H])=O)=O)=O)=O)=O |
安全信息
| 存储要求 | -20°C |
|---|
产品详情
产品简介
EGF是一种有效的生长因子，可刺激各种表皮和上皮细胞的增殖。另外，EGF可抑制胃分泌，并参与伤口愈合。EGF通过称为c-erbB的受体发出信号，该受体是I类酪氨酸激酶受体。该受体还与TGF-α和VGF（痘苗病毒生长因子）结合。
产品用途
表皮生长因子(Epidermal Growth Factor,简称EGF )是广泛存在于哺乳动物体内的一类多肽物质。
体外研究
表皮生长因子(EGF)诱导的各种细胞蛋白酪氨酸磷酸化在含有外源性过氧化氢酶的A431细胞中被完全阻断。
体内研究
表皮生长因子(EGF)(渗透泵在8天内以10pg/天的速度输送)对雄性小鼠的伤口闭合具有非常显著的刺激作用。动物模型：C57BL6J和CBA小鼠(从背部中央切出0.5 cm2全厚背部伤口)剂量：10μg/天给药：渗透泵以10 pg/天的速度输送8天结果：在雄性小鼠中,在6天内对伤口闭合表现出高度显著(P<0.001)的刺激作用。
